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pentobarbital will lessen the level or effect of buprenorphine, lengthy-acting injection by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Keep an eye on Closely. Individuals who transfer to buprenorphine long-performing injection from transmucosal buprenorphine coadministered with CYP3A4 inducers should be monitored to mak